Cisco Cisco AnyConnect Secure Mobility Client v2.x Information Guide

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Supported VPN Platforms, Cisco ASA Series
Clientless SSL VPN for Computer OSs
5
1,2,3 
OS X 10.9, 10.10, and 10.11 do not support Smart Tunnel.
Java Compatibility
Java Runtime Environment 1.5 to 1.7, and Java 8, is supported where applicable. 
On Mac OS X, Apple’s JRE is supported. 
Enterprise Applications Supported
The ASA 9.6 clientless SSL VPN core rewriter has been verified with the following applications:
Microsoft SharePoint 2003, 2007, 2010 and 2013
Microsoft Outlook Web Access 2003, 2007, 2013
Microsoft Outlook Web App 2010
Domino Web Access (DWA) 8.5 and 8.5.1
Citrix Metaframe Presentation Server 4.x
Citrix XenApp Version 5 to 6.5
Citrix XenDesktop Version 5 to 5.6, and 7.5
VMware View 4
XenDesktop 7.6
Note: 
There is no WebSocket support through rewriting.
Smart Tunnel Notes
Smart tunnel supports all applications not supported by the core rewriter. 
Smart tunnel is supported on Windows and Mac OS X platforms only. 
OS X 10.9, 10.10, and 10.11 do not support Smart Tunnel.
Smart tunnel does not support Linux. 
Smart tunnel is supported on x86 and x64 architectures only, Itanium and Power PC architectures are not 
supported. 
Smart tunnel requires Active X or Java enabled browsers.
Smart tunneling is not intended to restrict network access to only internal resources.
Additional 
Other Application Notes
The following application notes apply to clientless SSL VPN on ASA Release 9.6:
WebFolder has been superseded by Java file browser. 
Plug-ins are supported on Windows and Mac OS X platforms only. Plug-ins are not supported on Linux. 
The ActiveX version of the RDP plug-in is only supported on 32-bit browsers on Windows platforms.
The ICA plug-in does not support XenDesktop
Port forwarding is only supported on 32-bit browsers on Windows platforms. Additional 
 apply.