Cisco Cisco Email Security Appliance C680 User Guide

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Cisco IronPort AsyncOS 7.5 for Email Configuration Guide
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Chapter 8      Anti-Spam
Figure 8-6
IronPort Anti-Spam Global Settings
Additional Steps
Once you have enabled IronPort Anti-Spam, enable SenderBase Reputation 
Service scoring, even if you are not rejecting connections based on SenderBase 
Reputation Scores. For more information on enabling SBRS, see