Xerox 3400 Guida Di Riferimento

This toner material has been evaluated by Xerox Corporation. The toxicity data noted 
below is based on test results of similar reprographic toner materials

Additional Information: The results obtained from a Xerox-sponsored Chronic Toner 
Inhalation Study demonstrated no lung change in rats for the lowest (1 mg/m

3

) 

exposure level (i.e. the level most relevant to potential human exposure). A very 
slight degree of fibrosis was noted in 25 percent of the animals at the middle 
(4 mg/m

3

) exposure level, while a slight degree of fibrosis was noted in all the 

animals at the highest (16 mg/m

3

) exposure level. These findings are attributed to 

"lung overloading," a generic response to excessive amounts of any dust retained in 
the lungs for a prolonged period. This study was conducted using a special test toner 
to comply with EPA testing protocol. The test toner was ten times more respirable 
than commercially available Xerox toner, and would not be functionally suitable for 
Xerox equipment.

1

 XEL - Xerox Exposure Limit

N.A. - Not Applicable
N.E. - None Established
N.D. - Not Determined

>5 g/kg (rats) practically non-toxic.

>5 g/kg (rabbits) practically non-toxic.

>5 mg/l (rats, 4 hr exposure) practically non-toxic.

>20 mg/l (rats, calculated 1 hr exposure) non-poisonous,

Not an irritant. 

Skin Sensitization: Not a sensitizer.
Skin Irritation:

Not an irritant.

Non-irritating/non-sensitizing.

No evidence of mutagenicity detected in Ames Assay.

None present

 >1000 mg/l (fathead minnows/rainbow trout) non-toxic.

10mg/m

3

 (total dust)

15 mg/m

3

 (total dust)

5 mg/m

3

 (respirable dust)

N.E.

N.E.

2.5 mg/m

3

 (total dust)

0.4 mg/m

3

 (respirable dust)