Cisco Cisco Email Security Appliance C190 Installation Guide

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Plan the Installation
To defend your email system against spam, malware, phishing, 
and other threats, the Cisco C190 appliance must be installed at 
the perimeter of your network. It needs to be the first appliance 
with an IP address that can access the Internet.
Plan for your network configuration to look something like this:
Message Security 
SenderBase Reputation Filtering:
Enable/Disable
Cisco Anti-Spam Scanning Engine:
Enable/Disable
McAfee Anti-Virus Scanning Engine: 
Enable/Disable
Sophos Anti-Virus Scanning Engine:
Enable/Disable
Virus Outbreak Filters:
Enable/Disable
Advanced Malware Protection 
 
Scanning Engine
Enable/Disable